3 3 Diindolylmethane Powder
English name: 3,3'-Diindolylmethane
White to off-white crystalline powder
CAS No.: 1968-05-4
Two Factories & Three production lines
GMP standard workshop & two independentlaboratories
Certifications: HACCP, Halal,ISO9001,PAHS Free,NON-GMO,KOSHER,SC
3 3 Diindolylmethane Powder Supplier:
Guanjie Biotech's 3 3 diindolylmethane powder is White to off-white crystalline powder. DIM has good solubility in most organic solvents ( ethanol, ethyl acetate, chloroform, etc.), but poor solubility in water. Our factory has independent production line, welcome to enquiry: info@gybiotech.com.
Advantages:
The 3 3 diindolylmethane bulk powder developed by our company has the following advantages:
● Ash content<0.5%.
● Specification requirement 1%
● Content: 99%
● Appearance: Pure white. White to pink for other families on the market.
Moisture:0.5%.
COA
Items | Specifications | Result | Test Method |
Appearance | Off-white to white crystalline powder | Conform | Visual |
Odor, Taste | Characteristic | Conform | Sensory |
Particle Size | 98% pass 80mesh | Conform | GB/T 5507-2008 |
Content | ≥99.0% | 99.43% | HPLC |
Loss on drying | ≤0.5% | 0.3% | GB 5009.3-2016 |
Melting Point | 165.0℃~169℃ | 167℃ | GB/T 21781-2008 |
Heavy Metals | ≤10 ppm | Conform | GB 5009.74-2014 |
Pb | ≤2 ppm | Conform | GB 5009.12-2017 |
As | ≤2 ppm | Conform | GB/T 5009.11-2014 |
Benzene | Without Benzene | Not detected | GB 5009.262-2016 |
Solvent Residue | Methanol≤3000ppm | Conform | GB 5009.262-2016 |
Total Plate Count | ≤1000cfu/g | Conform | GB 4789.2-2016 |
Total Yeast & Mold | ≤100 cfu/g | Conform | GB 4789.15-2016 |
E. Coli | Negative | Negative | GB 4789.38-2012 |
Salmonella | Negative | Negative | GB 4789.31-2016 |
Staphylococcus aureus | Negative | Negative | GB 4789.10-2016 |
Chemical Properties
1.Stability:
Under normal temperature and pressure, DIM has good chemical stability, not easy to decompose or react.
2.Acid-base properties:
Due to the indole group in the structure, DIM may decompose and react under strong acid or alkali environment.
- Photosensitivity:
DIM may decompose under strong light irradiation, so it is necessary to avoid light during storage and use.
- Redox Reaction:
DIM contains reactive nitrogen atoms which may undergo redox reactions in the presence of certain oxidising or reducing agents.
- Conjugated Systems:
Due to the presence of an aromatic ring in the structure, 3 3 diindolylmethane powder may participate in some reactions specific to aromatic compounds, such as electrophilic substitution reactions.
Efficacy:
- Treats acne
Does your acne appear at the same time in each menstrual cycle. Acne that grows deep and painful is a cystic pimple that does not break easily and grows along the chin, jawline or cheeks. If this is the case with acne, it may benefit from the effects of DIM.
Hormonal acne is caused by an imbalance of good estrogen, bad estrogen and testosterone. When you supplement with DIM, it blocks the bad estrogen metabolic pathways and strengthens the good estrogen and testosterone. When everything is balanced, it is beneficial in supporting the skin to stay clear and healthy.
- Testosterone Supplementation and DIM
Everyone has testosterone in their bodies - men and women need it for cardiovascular health, bone density, skin quality, mental health, and more. And by the age of about 45, testosterone usually drops to the point where some physiological processes don't function properly.
There is a substance in the body called aromatase. It converts some of the testosterone in our body. Whether it is naturally occurring or supplemented, aromatase converts some of the testosterone into estrogen. It has all the effects of natural estrogen. 3 3 diindolylmethane powder inhibits the aromatase enzyme, allowing more testosterone to be freely available in your system. It is good for the heart, bones, skin and brain. Plus, when the aromatase enzyme can't convert testosterone into harmful estrogen metabolites, you won't experience the symptoms triggered by estrogen dominance. Things like acne and mood swings.
- Diindolylmethane and the fight against cancer
DIM bulk powder helps prevent and treat breast and prostate cancer. Studies on animals have also found that DIM can prevent cancer cells from replicating and spreading. exactly how DIM helps prevent and treat cancer is not known; DIM inhibits the formation of new blood vessels. Tumours require the growth of new blood vessels to provide the nutrients necessary for tumour growth. Therefore, by stopping the growth of new blood vessels, DIM can help eliminate tumours.
- DIM for weight loss
There are several possible reasons why people experience weight loss after supplementing with Diindolylmethane bulk powder. First, bad estrogen signals to your body that it needs to keep the weight off. This is especially true if you have fat accumulation in your hips and thighs. But if estrogen metabolites are balanced, the body doesn't have to retain excess fat. Second, DIM and its precursor I3C inhibit lipogenesis. That is, the formation of new fat cells. It also stimulates the burning metabolism of fat cells in the body, aiding in weight loss.
- Diindolylmethane and Estrogen
Some studies have reported that DIM helps balance estrogen and testosterone hormones. When estrogen is broken down in the body, beneficial or harmful estrogen metabolites are formed. And 3 3 diindolylmethane powder helps the body break down estrogen into beneficial types. The beneficial estrogen metabolites have antioxidant properties that help protect the heart and brain from free radical damage. Diindolylmethane also reduces levels of harmful estrogen metabolites at the same time. This has been linked to an increased risk of obesity, breast and uterine cancer. Other problems associated with harmful estrogen metabolites include depressed mood and breast pain in women and decreased libido in men.
DIM Dosage and Contraindications
DIM is usually available in 100 to 200 mg capsule formulations. Because of the potential for detox-related symptoms, it is recommended to start with a low dose. Take 100mg daily or every other day until you no longer experience detoxification symptoms. Then maintain or increase the dose based on goals. Bodybuilders who use DIM to counteract the effects of testosterone supplements converting to estrogen usually take 400mg per day.
Storage Methods
- Store away from light:
3 3 diindolylmethane powder is sensitive to light. Prolonged exposure to light may cause it to degrade. It should be stored in containers protected from light, preferably in opaque or dark-coloured bottles.
- Low Temperature Storage:
It is recommended that diindolylmethane be stored at low temperatures. It is generally best stored in a refrigerator at 2-8°C. Avoid storing in a high temperature environment as high temperatures accelerate its degradation.
- Dry environment:
Diindolylmethane should be stored in a dry environment to avoid moisture. Humid environments may cause changes in physical properties and chemical degradation.
- Sealed Storage:
Use sealed containers to store diindolylmethane. Avoid contact with moisture and oxygen in the air. Small packets or ziplock bags with desiccants may be used to increase preservation stability.
- Avoid frequent opening:
Minimise the number and duration of openings to reduce its exposure to air and thus prolong its useful life.
Precautions
- Chemical Stability:
3 3 diindolylmethane powder may react chemically under acidic or alkaline conditions. Avoid contact with acidic or alkaline materials during storage.
- Safety:
Wear gloves and protective eyewear when handling diindolylmethane. Avoid direct contact with skin and eyes. In case of inadvertent contact, flush immediately with plenty of water.