Product Information

Spermidine Trifluoroacetate is an important polyamine compound. Spermidine trihydrochloride powder is widely present in cells and participates in a variety of biological processes. Its role in cell proliferation, anti-aging, and anti-oxidation has received increasing attention.

Chemical structure

Spermidine Trifluoroacetate is a salt compound formed by the combination of trifluoroacetic acid, TFA and spermidine. Spermidine is a polyamine compound containing a triamine group. Structurally, it is synthesized by decarboxylation reaction of amino acid precursors - guanidine and putrescine. There are two amine groups and one aminomethyl group in its molecule. This structure has high hydrophilicity and charge distribution characteristics in cells.

Source

Spermidine is a natural polyamine compound that is widely present in animal and plant cells. It is mainly synthesized by enzymatic reaction of guanidine compounds (such as arginine) or humus-based raw materials (such as putrescine). Spermidine Trifluoroacetate is a derivative obtained by the reaction of spermidine with fluoroacetic acid in chemical synthesis. It is often used in research and biomedicine.

Functions

• Cell proliferation and differentiation

Spermidine trihydrochloride powder plays a key role in cell growth and division. It promotes cell proliferation and differentiation by promoting DNA synthesis, regulating the cell cycle and enhancing protein synthesis. Studies have found that spermidine can stabilize cell structure and ensure its normal function by binding to DNA, RNA and other cellular macromolecules.

• Anti-aging effect

In recent years, the potential of spermidine as an anti-aging substance has gradually been revealed. Scientists have found that spermidine can activate the autophagy mechanism, delay the aging process, and enhance the repair ability of cells. In many aging-related biological processes, high concentrations of spermidine are associated with young cell performance. This shows its important role in anti-aging.

• Antioxidant effect

Spermidine can effectively scavenge free radicals and reduce oxidative stress damage to cells. It strengthens the cell's antioxidant defense system and delays the accumulation of oxidative damage by increasing the activity of intracellular antioxidant enzymes, such as superoxide dismutase SOD and Catalase.

• Regulate autophagy

Autophagy is an important degradation process in cells. It can help cells remove damaged organelles and proteins and maintain the stability of the intracellular environment. Spermidine trihydrochloride powder regulates the expression of autophagy-related genes. Such as Atg genes. It can promote the occurrence of autophagy, thereby maintaining cell health and reducing the risk of aging and disease.

• Neuroprotective effect

Spermidine has also been found to have significant neuroprotective effects. Studies have shown that spermidine bulk powder can protect the nervous system from damage by reducing oxidative stress in neurons, improving mitochondrial function, and reducing inflammatory responses.

Application

• Application in biomedical research

As a research tool, Spermidine Trifluoroacetate is widely used in cell biology, molecular biology, and biochemistry. It has good stability and is easy to dissolve. Therefore, it is often used in cell culture experiments, protein synthesis research, DNA/RNA extraction and other experiments.

•Anti-aging health products

As a potential anti-aging substance, spermidine has gradually been used in health products. Many studies have shown that spermidine trihydrochloride powder can delay the aging process by improving the autophagy ability of cells, reducing oxidative stress, and promoting cell repair. Anti-aging health products with spermidine as an ingredient have appeared on the market, especially in delaying aging, enhancing immunity and improving skin quality. Guanjie Biotech is a manufacturer and we can provide raw materials for your products.

• Clinical application

In clinical practice, the anti-aging, antioxidant and neuroprotective effects of spermidine trifluoroacetate have opened up new application prospects for its treatment of certain diseases. For example, spermidine can be used as a potential auxiliary therapeutic drug to delay the progression of Alzheimer's disease and Parkinson's disease and improve patients' cognitive function and motor ability. In addition, spermidine may also play a role in the treatment of chronic diseases such as cancer and diabetes.

• Food additives

Spermidine bulk is a natural active ingredient. Its antioxidant and anti-aging functions also make it a potential additive in food and beverages. It can help extend the shelf life of food, improve the nutritional value of food, and enhance the health function of food.

Safety and side effects

Spermidine trihydrochloride powder has shown significant biological activity in many studies. However, its safety for long-term use still needs further clinical research verification. Current research focuses on the short-term use of spermidine and its performance in animal experiments. There is currently insufficient clinical evidence to support its safety for long-term use. Although no obvious toxicity was found in some high-dose experiments, it still needs to be used with caution. Especially in pregnant women, lactating women and patients with certain special diseases.

Spermidine Trifluoroacetate is an important bioactive substance. Its significant effects on cell proliferation, anti-aging, and anti-oxidation have gradually become a research hotspot in biomedicine and health products.Guanjie Biotech is a bulk spermidine trihydrochloride manufacturer, we can provide you wholesale spermidine trihydrochloride powder. If you want add our bulk spermidine to your products, welcome to enquiry us:info@gybiotech.com.